Priligy is a prescription medication used to treat the symptoms of premature ejaculation in adult men medically diagnosed with this condition. The main active ingredient, dapoxetine, is a potent selective serotonin reuptake inhibitor. Priligy is commercially available as oral tablets of two dosages: 30 mg and 60 mg. Read more about the indications and features of use in the instructions.

How Common Is Premature Ejaculation: Stats and Figures

Premature ejaculation (PE) is a common sexual issue affecting men, causing discomfort and distress for both partners. Experts report that around 25-30% of men experience PE at some point in their lives, although individual studies reveal that the number of male patients suffering from this condition might be as high as 50%.

Here are some additional statistics showing the prevalence and impact of PE:

  • About 1 in 3 men in a sexually active age of 18-59 experiences incidents of PE
  • PE is usually diagnosed in men who  are unable to delay ejaculation long enough for their partner to achieve orgasm in 50% of intercourse attempts
  • In men with life-long PE, the ejaculation time is usually less than 1 minute; in men with acquired PE this time is less than 3 minutes
  • 30–60% of men diagnosed with erectile dysfunction (ED) also have PE
  • Over 40% of pre-divorce counseling cases deal with issues related to premature ejaculation

What Causes Premature ejaculation?

The exact reason why PE occurs is unknown, but the onset and persistence of this condition are believed to be influenced by several factors, including biological, chemical, psychological, and lifestyle ones, or – sometimes – their combination:

  • Psychological factors of PE: performance anxiety, stress, depression, lack of confidence, or relationship issues
  • Biological factors of PE: abnormal hormone levels, genetic predisposition, thyroid gland problems, or abnormal reflex activity of the ejaculatory system
  • Chemical factors of PE: irregularities in the activity of neurotransmitters (serotonin) within the central nervous system
  • Lifestyle factors of PE: unhealthy lifestyle habits, lack of stress coping mechanisms, and substance abuse

Knowing which factors are at play in any given PE case is important to correctly diagnose the condition and find the most optimal treatment for it.

General Info Priligy

The medicine’s active ingredient is dapoxetine, which functions as a selective serotonin reuptake inhibitor. It works by increasing serotonin levels in the brain, thus delaying ejaculation. The medication comes in oral tablet form, with dosages typically available in 30 mg and 60 mg strengths. Doctors recommend starting with the lower dose to assess the patient’s overall response and tolerance of the drug and then increasing it as necessary.

Generic Priligy tablets are not intended for continuous daily use or for use by people who do not have symptoms of premature ejaculation. Priligy should be taken 1 to 3 hours before anticipated sexual activity and not more often than once every 24 hours. The drug can be taken with or without food and accompanied with a glass of water.

Side Effects and Ways to Reduce Them

The most common side effects associated with the use of Priligy include nausea, headache, dizziness, diarrhea, and insomnia. To minimize discomfort, patients should not exceed the prescribed dosage of this medicine and report any adverse effects to their doctor immediately.

Other recommendations that might help make the use of Priligy more manageable include:

  • staying well hydrated while using this drug
  • not using any recreational drugs, sleeping pills, or alcohol when taking Priligy
  • taking paracetamol to cope with headaches caused by Priligy
  • having a light meal before taking Priligy to reduce the possibility of nausea
  • avoiding grapefruit juice when taking Priligy to keep the concentration of this drug stable and within the norm

Experiencing symptoms like irregular heartbeat, mental confusion or disorientation, loss of consciousness, or signs of allergic reaction to the drug should be a reason to seek urgent medical help.

What Other Medicines Affect Priligy?

There are some known unsafe interactions of Priligy with other drugs and certain herbal remedies. Patients need to inform their prescribing physician about taking or having recently taken any of the following:

  • SNRI antidepressants (duloxetine)
  • SSRI antidepressants (fluoxetine, paroxetine, sertraline)
  • antipsychotic medications (thioridazine)
  • opioid analgesics (tramadol)
  • tricyclic antidepressants (clomipramine, amitriptyline)
  • mood stabilizers (lithium)
  • MAOI antidepressants (phenelzine, tranylcypromine, isocarboxazid)
  • selective MAO-B inhibitors (rasagiline, selegiline)
  • oxazolidinone antibiotics (linezolid)
  • natural antidepressants (St John’s wort)
  • amino acid supplements (tryptophan)

The above list does not feature all the drugs Priligy can interact with – sometimes unsafely. Patients should always consult their healthcare provider to ensure the safe and effective use of Priligy when combined with other medications.

Can Priligy Be Taken by Anyone and At Any Age?

Priligy is recommended for use only in male patients aged 18-64 medically diagnosed with premature ejaculation (PE). In some cases, Priligy can be prescribed to men in the 65+ age group but only when age-related health concerns and individual medical history have been thoroughly evaluated by a licensed healthcare professional and the drug has been deemed safe for use in such patients. The effectiveness and safety of this drug have not been studied or established in male patients under 18 years or in women of any age.

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